The effect of rTMS combined with repeated magnetic stimulation of Taichong (LR3) on depression: a randomized controlled trial

Phase 1

• Conditions: depression

• Registration Number: ITMCTR1900002752
• Lead Sponsor: Shaanxi Provincial Chinese Medicine Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Sign the informed consent voluntarily;
2. Meet the western medicine diagnosis standard of depression;
3. It conforms to the diagnostic standard of depression in traditional Chinese medicine;
4. Hamilton Depression Scale 7 < HAMD-17 <= 24;
5. Aged 18-65 years old.

Exclusion Criteria

1. Those diagnosed as other mental diseases, such as panic disorder, obsessive-compulsive disorder, schizophrenia, hypochondriasis, etc;
2. The patients who had used western medicine of anti anxiety, anti depression, anti psychosis and the same kind of traditional Chinese medicine in the first 4 weeks before entering the group;
3. Taking antidepressants or having antidepressant pharmacological effect without washout;
4. Pregnant or preparing pregnant or lactating women;
5. Hyperthyroidism, coronary heart disease, hypertension, irritable bowel syndrome and other endocrine, cardiovascular and digestive system diseases with depression;
6. Patients with organic mental disorders, psychoactive substances, non addictive substances and postpartum depression;
7. Patients who have a history of suicide or a tendency to commit suicide, with a suicide score >= 1 in HAMD-17;
8. Patients who participated in or are participating in other clinical trials within 1 month before enrollment;
9. Magnetic metal objects implanted near the head or in the brain, such as intracranial stent, cochlear implant, etc;
10. No monitoring or failure to complete the clinical study.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HAMD-17;SCL-90;PHQ-15;

Secondary Outcome Measures

Name	Time	Method
PSQI;rMT;