ormobaric hyperoxia preconditioning ameliorates cisplatin nephrotoxicity: a pilot prospective case-control study
Not Applicable
Completed
- Conditions
- Acute renal failure.Acute renal failure
- Registration Number
- IRCT201102065775N1
- Lead Sponsor
- ephrology and Urology Research Center, Baqiyatallah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 21
Inclusion Criteria
the patients who treated with cisplatin due to cancer
Exclusion criteria: The patients who had chronic obstructive lung disease, pneumothorax, upper respiratory infection, fever, viral infection, history of seizure, optic nerve inflammation, history of ear surgery and history of heavy cigarette smoking were excluded from this study. None of female patients was pregnant.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum Creatinine. Timepoint: 0, 6,24,48. Method of measurement: Serum creatinine measurment previous day and 6, 24, 48 houre after Hyperoxia preconditioning.
- Secondary Outcome Measures
Name Time Method EGFR decrementation. Timepoint: -1, 0, 2, 5 days after threatment. Method of measurement: plasma creatinine for GFR estimation in all patients in-1, 0, 2 and 5 days after cisplatin exposures.