Use of fentanyl vs dexmedetomide as adjuvant to 0.5% Bupivacaine hyperbaric in spinal anaesthesia for total hip replacement surgeries.

Phase 4

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/10/058679
• Lead Sponsor: Peoples college of medical science

Brief Summary

We will be comparing two adjuvant dexmedetomidine and fentanyl when added to 0.5% Bupivacaine in patient  posted for tolat hip replacement surgeries in spinal anaesthesia for purpose of trial.

Since there are no such study has been done in Central india.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-10-14
• Study Start: 2023-10-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1Age > 18 years 2ASA grade1 and 2 3Scheduled for elective total Hip replacement surgeries under subarachnoid block.

Exclusion Criteria

• 1Lack of patient’s consent.
• 2Age <18yrs 3ASA grade 3 and more.
• 4Patients with local skin site infections.
• 5Patients with hypersensitivity to any of the drugs used.
• Pregnant and lactating mothers.
• History of serious pulmonary disease, ischemic heart disease, renal/hepatic dysfunction, coronary artery, or cervical spine disease and patients with abnormal coagulation profile.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post operative relief in pain	5 hrs

Secondary Outcome Measures

Name	Time	Method
Heart rate changes	5 hours

Trial Locations

Locations (1)

Peoples hospital; 🇮🇳 Bhopal, MADHYA PRADESH, India

Peoples hospital

🇮🇳Bhopal, MADHYA PRADESH, India

Ved jain

Principal investigator

08802977828

vedjain2004@yahoo.co.in