FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients

Not Applicable

Recruiting

• Conditions: Exercise; Brain Tumor, Primary
• Interventions: Other: High-Intensity Interval Training (HIIT)

• Registration Number: NCT06282562
• Lead Sponsor: Amsterdam UMC, location VUmc

Brief Summary

The FeelFit study aims to assess the effectiveness of High-Intensity Interval Training (HIIT) in improving self-reported physical fitness in adult brain tumor patients during periods of stable disease, as compared to a waiting-list control group. Furthermore, several secondary and exploratory outcomes will be evaluated. The study is part of the GRIP (GuaRding quality survivorshiP) project, which aims to improve quality of life in brain tumor patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-02-06
• Study First Submitted QC: 2024-02-20
• Study First Posted: 2024-02-28
• Status Verified: 2024-03
• Study Start: 2024-03
• Last Update Submitted: 2024-03-04
• Last Update Posted: 2024-03-06
• Primary Completion: 2026-08-15
• Study Completion: 2026-08-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• reduced self-reported physical fitness;
• minimum age of 18 years;
• diagnosed with a primary brain tumor;
• stable disease, i.e. no signs of radiological or clinical tumor progression;
• no oncological treatment for at least two months prior to inclusion;
• able to speak, read and write in Dutch.

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Exclusion Criteria

• Karnofsky Performance Score < 70;
• already participated in a HIIT program < 1 month prior;
• contraindication of exercise.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
HIIT	High-Intensity Interval Training (HIIT)	The intervention group will perform High-Intensity Interval Training (HIIT), consisting of two supervised exercise sessions per week on a stationary bike, for 12 weeks. In addition, participants will receive information on general guidelines for weekly physical activity levels and will be asked to keep an exercise diary.

Primary Outcome Measures

Name	Time	Method
Self-reported physical fitness	Baseline versus post-intervention (12 weeks) and versus follow-up (12 weeks and 6 weeks follow-up)	Self-reported physical fitness is measured using the first question of the International Fitness Scale (IFIS) on general physical fitness, on a 5-point scale where a higher score corresponds to better self-reported physical fitness.

Secondary Outcome Measures

Name	Time	Method
Self-reported fitness	Baseline versus post-intervention (12 weeks) and versus follow-up (12 weeks and 6 weeks follow-up)	In addition to the first question of the International Fitness Scale (IFIS), the other questions about cardiorespiratory fitness, muscle strength, speed and flexibility will also be asked as secondary outcomes.
VO2max	Baseline versus post-intervention (12 weeks)	Physical fitness defined as the maximal oxygen uptake measured with a cardiopulmonary exercise test.

Trial Locations

Locations (1)

VU University Medical Centers, location VUmc; 🇳🇱 Amsterdam, Netherlands