Administration of low dose Ketamine and/or Dexmedetomidine for attenuation of post-operative pain following laparoscopic cholecystectomy
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/10/059009
- Lead Sponsor
- Sonia Naorem
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients of either sex
2. Age group 18-60years
3. Patients of American Society of Anesthesiology (ASA) grade I and II
4. Undergoing elective laparoscopic Cholecystectomy
Exclusion Criteria
1. Conversion to open cholecystectomy
2. Patients included in another study
3. Patients with history of significant cardiovascular disease (eg MI within the past 6months)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the post-operative rescue analgesic requirements in the first 24hoursTimepoint: Outcome to be assessed at 24hours post-op
- Secondary Outcome Measures
Name Time Method 1. The Sedative effectsTimepoint: 30min post-op <br/ ><br>1hour post-op <br/ ><br>2hour post-op <br/ ><br>6hour post-op <br/ ><br>12hour post-op <br/ ><br>24hour post-op;2. The time of first rescue analgesic requestTimepoint: When the VAS score more than or equal to 4;Other side effects like dizziness, nausea, vomitingTimepoint: Anytime within the first 24hours post-op