Transcutaneous electromyography of the diaphragm of newborn infants

Withdrawn

• Conditions: Control of breathing; diaphragm activity; 10028971

• Registration Number: NL-OMON41440
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 240

Inclusion Criteria

Premature neonates GA < 37 weeks and healthy term infants
Non-invasive respiratory support or no respiratory support
Informed consent of one or both parents

Exclusion Criteria

Congenital malformation of thorax, heart and/or lungs
Non-invasive or invasive (endotracheal) ventilation

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Feasibility and reproducibility of tc-dEMG on premature neonates<br /><br>- Differentiation between central versus obstructive apneas with tc-dEMG.<br /><br>- The effect on diaphragm activity of an upload dose Caffeine or Dopram .<br /><br>- The effect on diaphragm activity when changing respiratory support from nCPAP<br /><br>to 'flowsnor'.<br /><br>- Predictive values of success or failure by change from nCPAP to 'flowsnor'.<br /><br>- Which role plays the diaphragm during neonatal pulmonary transition.<br /><br>- Detection of spontaneous breaths by transcutaneous dEMG.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>