ISRCTN14865526CompletedNot Applicable
The influence of epidural blockade with ropivacaine on the pharmacokinetics and pharmacodynamics of propofol sedation in patients
eiden University Medical Center (Netherlands)0 sites28 target enrollmentStarted: January 30, 2014Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 28
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. American Society of Anesthesiologists (ASA) class I-II
- •2. Age 18-65 years
- •3. Patients scheduled for surgery requiring epidural anaesthesia and sedation
Exclusion Criteria
- •1. Patients with a body mass index (BMI) >30
- •2. Participation in a trial on investigational drugs within 3 months prior to the study
- •3. Known history of hepatic, renal disease or other disease as judged by the investigators
- •4. Bleeding or coagulation disorders
- •5. Patients receiving chronic analgesic therapy
- •6. Patients using alpha-blockers
- •7. Pregnancy or lactation
- •8. Alcohol or drug abuse or history of alcohol/drug abuse
- •9. Documented or suspected soybean protein and/or drug allergy
- •10. Allergy for amide-type local anesthetics
Investigators
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