NL-OMON34206已完成不适用
The influence of epidural blockade with ropivacaine on the pharmacokinetics and pharmacodynamics of propofol sedation - Epidural ropivacaine and the pharmacokinetics / -dynamics of propofol
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •ASA class I-II
- •Age 18-65 years
- •Patients scheduled for surgery requiring epidural anaesthesia and sedation.
排除标准
- •Patients with a BMI >30.
- •Participation in a trial on investigational drugs within 3 months prior to the study.
- •Known history of hepatic, renal disease or other disease as judged by the investigators.
- •Bleeding or coagulation disorders
- •Patients receiving chronic analgesic therapy.
- •Patients using β-blockers
- •Pregnancy or lactation.
- •Alcohol or drug abuses or history of alcohol/drug abuses.
- •Documented or suspected soybean protein and/or drug allergy or amide type local anesthetic allergy
研究者
相似试验
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Epidural blockade affects the pharmacokinetics of propofol in surgical patientsThe effect of epidural analgesia with ropivacaine on the pharmacokinetics and pharmacodynamics of propofol in patientsSurgeryISRCTN14865526eiden University Medical Center (Netherlands)28
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Control of post operative pain after lumbar spine surgery : Epidural dexmedetomidine versus clonidine as adjuvants to ropivacaine.CTRI/2017/10/010167IPGMER Hospital Kolkata44