NL-OMON48792
Completed
Not Applicable
Evolution of mitochondrial dysfunction and hypermetabolic inflammatory status in septic Intensive Care Unit patients - Mitochondria Intensive Care (MIC)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- blood poisoning
- Sponsor
- Wageningen Universiteit
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Septic ICU patients:
- •\- 18\+ years of age
- •\- Diagnosed with sepsis, not origniated from the urinary system
- •Control patients:
- •\- Short\-stay hospitalised patients (e.g. admission for one day), or patients
- •admitted to the outpatient clinic of Gelderse Vallei Hospital
- •\- Free of sepsis
- •\- Metabolically healthy
- •\- Age (\+/\- 2 years) and gender\-matched
Exclusion Criteria
- •\*Only applicable for septic ICU patients
- •\*\*Comprehensively described in appendix of the protocol
- •(All pre\-ICU admission notes are not applicable to control patients), •
- •Patients referred from another ICU
- •Patients with a haemoglobin level lower than 5,5 mmol/lL\*
- •Patients with a history of solid organ or bone marrow transplant
- •Patients with active autoimmune disease involving the lung, heart, liver,
- •small or large intestine, or neuromuscular system (e.g., myasthenia gravis,
- •multiple sclerosis) AND currently requiring systemic immunosuppressive therapy
- •Patients whom experienced a significant medical or surgical event leading to
Outcomes
Primary Outcomes
Not specified
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