Study of the association between abnormalities in mitochondrial function and Autism Spectrum Disorder (ASD): Can Ayurvedic herbs, that are used to improve intellect, reverse this?
Phase 4
- Conditions
- Health Condition 1: F840- Autistic disorder
- Registration Number
- CTRI/2021/07/035048
- Lead Sponsor
- Inter University Centre for Biomedical Research and Super Speciality Hospital IUCBR and SSH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Idiopathic cases of autism without any other developmental and neurological diseases
Age-matched controls without ASD or any other developmental disorders
Exclusion Criteria
Subjects with Fragile-X syndrome and gross chromosomal aberrations and other neurodevelopmental and neurological diseases
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reversal of mitochondrial dysfunction and associated symptoms found in autistic children <br/ ><br>Reversal of behavioral phenotype in autistic childrenTimepoint: At baseline, after 2 months and 3 months
- Secondary Outcome Measures
Name Time Method Assessing severity of autism symptoms using Childhood Autism Rating Scale, Autism Treatment Evaluation Checklist <br/ ><br>Mitochondrial functional analysis <br/ ><br>Platelet neurotransmitter analysisTimepoint: Baseline, after 2 and 3 months