Is There Room for Butter in a Healthy Diet?

Not Applicable

Completed

• Conditions: Atherosclerosis
• Interventions: Other: Danish butter; Other: Olive oil

• Registration Number: NCT02116829
• Lead Sponsor: University of Copenhagen

Brief Summary

The aim of this study is to examine the effects in humans of a moderate butter intake on risk markers of cardiovascular disease compared to a diet with the same amount of olive oil (refined and therefore without polyfenols).

The primary parameters are total cholesterol, LDL- and HDL cholesterol and triglycerides. The secondary parameters are risk markers of diabetes type 2; plasma glucose and insuling as well as the inflammatory marker hs-CRP.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Status Verified: 2014-04
• Study First Submitted: 2014-04-15
• Study First Submitted QC: 2014-04-16
• Last Update Submitted: 2014-04-16
• Study First Posted: 2014-04-17
• Last Update Posted: 2014-04-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Sign written consent
• Age: 20-70 y
• BMI: 18.5 - 32 kg/m2
• Healthy men and women (with no known diseases)

Exclusion criteria

• Current or previously cardiovascular disease, high blood pressure
• Diabetes Mellitus or other severe chronic disease, including severe allergies
• Use of dietary supplements and blood donations prior to, and during the study
• Known or suspected abuse of alcohol, drugs or medication
• Pregnant or are planning pregnancy during the study period
• Extreme physical activity level (more than 10 hours tough physical activity pr. week)
• Participation in other research studies
• Inability, physically or mentally, to comply with the procedures required by the study protocol, as evaluated by the study staff

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Danish butter, dairy	Danish butter	-
Olive oil, refined	Olive oil	-

Primary Outcome Measures

Name	Time	Method
LDL cholesterol	5 weeks
HDL cholesterol	5 weeks
Triglycerides	5 weeks
Total cholesterol	5 weeks

Secondary Outcome Measures

Name	Time	Method
hs-CRP	5 weeks
Insulin	5 weeks
Glucose	5 weeks

Trial Locations

Locations (1)

Department of Nutrition, Exercise and Sports; 🇩🇰 Copenhagen, Frederiksberg, Denmark