Endoscopic Tri-Modal Imaging (ETMI) for the detection and classification of early colorectal neoplasia; a multi-center randomized controlled trial
Recruiting
- Conditions
- Colorectal, neoplasia, adenomas, Colonoscopy, Imaging, Detection, classificationDutch: colon, neoplasie, adenomen, coloscopie, imaging, detectie
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 234
Inclusion Criteria
Patients (>18 years) undergoing colonoscopic surveillance because of:
a. history of adenomatous polyps.
b. history of CRC.
c. Hereditary Non-Polyposis Colorectal Cancer
d. family history of CRC/adenomas
Exclusion Criteria
1. Poor bowel preparation;
2. Familial Adenomatous Polyposis, attenuated FAP, MYH associated polyposis or hyperplastic polyposis;
3. History of inflammatory bowel disease;
4. Presence of conditions precluding histological sampling of the colon (e.g. coagulation disorders, anticoagulant therapy).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of adenomas detected by ETMI versus conventional colonoscopy.
- Secondary Outcome Measures
Name Time Method 1. Number of adenomas detected by HRE versus conventional colonoscopy;<br>2. Miss rate of HRE as followed by AFI (additional yield of AFI);<br>3. Accuracy of NBI and AFI in discriminating non-neoplastic from neoplastic lesions (Kudo classification and color)