Effects of Training in Healthy Sedentary Subjects

Not Applicable

Completed

• Conditions: Sedentary Subjects
• Interventions: Other: Training

• Registration Number: NCT01183039
• Lead Sponsor: 5 Santé

Brief Summary

The purpose of this study is to understand underlying mechanisms of improved exercise tolerance in Healthy Sedentary Subjects after training program.

Detailed Description

Training protocol used is based on recommendations. A minimum of 20 sessions in 4-6 weeks were proposed. The exercise intensity of exercise corresponds to target heart rate at ventilatory threshold measured during incremental exercise test. Training at this intensity allowed us to individualize effort for each patient.

Study Timeline

• Study Start: 2008-05
• Study First Submitted: 2010-08-16
• Study First Submitted QC: 2010-08-16
• Study First Posted: 2010-08-17
• Primary Completion: 2010-12
• Study Completion: 2010-12
• Status Verified: 2012-09
• Last Update Submitted: 2012-09-03
• Last Update Posted: 2012-09-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• healthy Sedentary Subjects

Exclusion Criteria

• neuromuscular disease
• chronic heart failure
• diabetes
• renal diseases
• liver diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Ventilatory threshold	Training	Training at the ventilatory threshold
Metabolic threshold	Training	Training at the metabolic threshold

Primary Outcome Measures

Name	Time	Method
Effects of training program on mitochondrial function and oxidative stress	6 to 8 weeks

Secondary Outcome Measures

Name	Time	Method
Relationship between mitochondrial function, oxidative stress and exercise tolerance in COPD patients	6 to 8 weeks

Trial Locations

Locations (3)

Clinique du souffle La valonie; 🇫🇷 Lodeve, France

hopital Arnaud de Vilneuve; 🇫🇷 Montpellier, France

Clinique du souffle La solane; 🇫🇷 Osseja, France