To evaluate the effect of two different anesthetic agents on electroconvulsive therapy for psychiatric patients
Completed
- Conditions
- Patients suffering from mental disorder as per ICD 10 requiring Electroconvulsive therapy advised by Consultant Psychiatrist
- Registration Number
- CTRI/2016/01/006530
- Lead Sponsor
- Divya Mehta
- Brief Summary
The main aim of this study is to find an ideal induction agent for anaesthesia during modified electroconvulsive therapy .Etomidate has been found to prevent haemodynamic changes during seizure .It also increases seizure duration .The studies revealed that more is the seizure duration , more is the therapeutic efficacy of electroconvulsive therapy.An ideal anaesthetic agent should be able to minimise haemodynamic changes without significant effect on seizure duration. This study compares the effect of etomidate with propofol on haemodynamics as well as seizure duration .
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Patients suffering from a mental disorder as per ICD 10 necessitating Electroconvulsive therapy decided by Consultant Psychiatrist.
- ASA grade 1 and 2 patients BMI > 18 and <25 kg/m2.
Exclusion Criteria
- Patients with history of relevant drug allergy.
- Patients with severe cardiovascular or neurological or respiratory disorder.
- Patients with history of substance use or drug abuse.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean Blood Pressure Before induction , after administration of study drug , during seizure , 1 ,3,5 and 10 minutes after the seizure .
- Secondary Outcome Measures
Name Time Method Diastolic Blood pressure Before induction , after administration of study drug , during seizure , 1 ,3,5 and 10 minutes after the seizure O2 saturation(SpO2) Before induction , after administration of study drug , during seizure , 1 ,3,5 and 10 minutes after the seizure . Heart rate Before induction , after administration of study drug , during seizure , 1 ,3,5 and 10 minutes after the seizure . Systolic Blood Pressure Before induction , after administration of study drug , during seizure , 1 ,3,5 and 10 minutes after the seizure . Motor seizure duration Measured by stop watch by isolated arm technique.
Trial Locations
- Locations (1)
Government Medical College and Hospital , Chandigarh
🇮🇳Chandigarh, CHANDIGARH, India
Government Medical College and Hospital , Chandigarh🇮🇳Chandigarh, CHANDIGARH, IndiaDivya MehtaPrincipal investigator9780932491dimsymehta@gmail.com