Trans-muscular quadratus lumborum block for management of post-surgical pain after gall bladder resection

Phase 4

Not yet recruiting

• Conditions: Calculus of gallbladder with acutecholecystitis,

• Registration Number: CTRI/2023/05/052217
• Lead Sponsor: Dr Priyanka Dwivedi

Brief Summary

Thisproposed study is a prospectivedouble blind, randomized controlledtrial which will be conducted at All India Institute of Medical Sciences,Gorakhpur. In this study, we wish toinvestigate the effects of ultrasound-guided anterior/ trans -muscular QL block(TQLB), administered bilaterally, for post operative analgesia afterlaparoscopic cholecystectomy operations. Our hypothesis in this study is thatpatients who receive TQLB will have lower Visual Analogue Scale (VAS) valuesduring rest and activity than the placebo group.

Thistrial can provide information regarding efficacy and safety of anterior/ Trans-muscularQL block (TQLB) and its role in enhance recovery after surgery (ERAS) inlaparoscopic cholecystectomy.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-04-28
• Study Start: 2023-06-18

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

American Society of Anesthesiologists physical status (ASA) I and II, who are scheduled for laparoscopic cholecystectomy under general anaesthesia.

Exclusion Criteria

• 1.Patient’s refusal 2.Allergies to local anesthetic drugs, 3.body mass index (BMI) >35 Kg/m, 4.Significant cardiovascular disease, hepatic dysfunction or renal dysfunction 5.Coagulation abnormalities, 6.Infection in the intended intervention site, 7.history of laparotomy 8.Inability to communicate.
• 9.Chronic opioid usage.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the analgesic effect of trans-muscular quadratus block after surgery in the form of visual analogue scale (VAS) score at rest.	To evaluate VAS score at 6 hours after intervention

Secondary Outcome Measures

Name	Time	Method
1.To evaluate the analgesic effect of trans-muscular quadratus block in the form of visual analogue scale (VAS) score at rest and on coughing in 1st 24 hours	2.To compare the duration of block (The time to first analgesic request) which is defined as the time interval between end of LA injection and patients pain complaint (VAS 3).

Trial Locations

Locations (1)

All India Institute of Medical Sciences, Gorakhpur; 🇮🇳 Gorakhpur, UTTAR PRADESH, India

All India Institute of Medical Sciences, Gorakhpur

🇮🇳Gorakhpur, UTTAR PRADESH, India

Dr Priyanka Dwivedi

Principal investigator

8795453444

drpriyad1111@gmail.com