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Clinical Trials/ISRCTN93153804
ISRCTN93153804
Completed
N/A

Continuous positive airway pressure therapy withdrawal - a model to evaluate treatment modalities for sleep apnoea: a randomised controlled trial

niversity Hospital of Zurich (Switzerland)0 sites40 target enrollmentJuly 14, 2009
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ConditionsObstructive sleep apnoeaNervous System DiseasesSleep disorders

Overview

Phase
N/A
Intervention
Not specified
Conditions
Obstructive sleep apnoea
Sponsor
niversity Hospital of Zurich (Switzerland)
Enrollment
40
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 14, 2009
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity Hospital of Zurich (Switzerland)

Eligibility Criteria

Inclusion Criteria

  • •1\. Objectively confirmed obstructive sleep apnoea with an original oxygen desaturation index (ODI) (greater than or equal to 4% dips) of between 10 and 50/h
  • •2\. Currently greater than 10 oxygen desaturations (greater than or equal to 4% dips) during an ambulatory nocturnal pulse oximetry performed at the end of a 4\-night period without CPAP
  • •3\. Treated with CPAP for more than 12 months, minimal compliance 4 hours per night
  • •4\. Written informed consent
  • •5\. Aged 20 \- 75 years (inclusive), either sex

Exclusion Criteria

  • •1\. Previous ventilatory failure (awake resting arterial oxygen saturation less than 93% or arterial partial pressure of carbon dioxide \[PCO2] greater than 6 kPa)
  • •2\. Unstable, untreated coronary or peripheral artery disease, severe arterial hypertension (greater than 180/110 mmHg)
  • •3\. Previously diagnosed with Cheyne\-Stokes breathing
  • •4\. Current professional driver
  • •5\. Any sleep related accident
  • •6\. Aged less than 20 or greater than 75 years at trial entry
  • •7\. Mental or physical disability precluding informed consent or compliance with the protocol
  • •8\. Non\-feasible trial follow\-up (for example, distance from follow\-up centre, physical inability)

Outcomes

Primary Outcomes

Not specified

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