Study on the clinical effect and mechanism of Taijiquan training on patients with silent brain infarctio

Not Applicable

Recruiting

• Conditions: Silent brain infarction

• Registration Number: ITMCTR2100004725
• Lead Sponsor: The Second People's Hospital affiliated to Fujian University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Aged from 50 to 75 years old;
2. Meeting the diagnostic criteria of silent brain infarction and is diagnosed by MRI;
3. Magnetic resonance ASL perfusion imaging shows the decrease of cerebral blood flow (CBF);
4. Good understanding and language ability;
5. Voluntary participation, and sign the informed consent form.

Exclusion Criteria

1. With physical disability, organic diseases such as joints and muscles, or other sports contraindications;
2. With a history of allergy to iodine or other contrast media;
3. People with metal implants, MRI contraindications, or claustrophobia;
4. People with cognitive impairment with a score of less than 26 on the MoCA scale;
5. Combined with brain tumor, brain injury, cerebral hemorrhage, subarachnoid hemorrhage, intracranial infection, epilepsy, Parkinson's disease or other neurological diseases;
6. Combined with serious primary diseases such as heart, liver, kidney, blood system, endocrine system, or combined with malignant tumor;
7. Abnormalities such as pathological Q wave and depression or elevation of ST segment were found in ECG, and the possibility of organic heart disease was considered;
8. Those who spent more than 1 hour each week on regular exercise in the last 3 months before joining the group,and those who are unable to maintain regular exercise after joining the group;
9. Those who are participating in other clinical trials that affect the evaluation of the results of this study.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cerebral hemodynamic indexes;Imaging characteristics of SBI;

Secondary Outcome Measures

Name	Time	Method
SBI risk factors;Balance indexes;Health status of traditional Chinese medicine;Expression of circulating exosomes miRNA-143;