Prospective, randomized, monocentric study for the determination of device-related dead spaces under controlled ventilation under general anesthesia
Not Applicable
- Conditions
- Spine operations in prone position
- Registration Number
- DRKS00015797
- Lead Sponsor
- St. Josef- und St. Elisabeth- Hospital gGmbH Klinik für Anästhesiologie und operative Intensivmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
All patients who would like to receive general anaesthesia for orthopaedic surgery at the Catholic Hospital Bochum
- ASA 1-3
ASA
The Classification of the American Society of Anesthesiologists (ASA Classification I- IV) is a widely applied categorization of the preoperative status of patients. It has a good predictive value regarding perioperative morbidity and mortality.
Exclusion Criteria
- lack of clarification or consent
- pregnancy
- simultaneous participation in another study
- ASA IV or higher
- COPD with a pathological image
CO2 >50mmHg or a base excess of >8 or a respiratory acidosis pH < 7.35
- intolerance to sevoflurane (e.g. malignant hyperthermia or muscle disease), remifentanil or piritramide
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - end expiratory CO2 (et CO2)<br>- respiratory minute volume (AMV)
- Secondary Outcome Measures
Name Time Method - total dead volume (Vds in ml)<br>- alveolar ventilation (VTalv)<br> = Vds minus the aparative dead space percentage,<br>- Dead space quotients = dead space volume / exhaled breath volume (Vds/VTE)<br>- breathing rate (AF), ventilation pressures, lung compliance, resistance, breathing work (WOB)