Effect of Turner Syndrome on Number Sense

Not Applicable

Withdrawn

• Conditions: Turner Syndrome
• Interventions: Behavioral: ANS training

• Registration Number: NCT03459651
• Lead Sponsor: Stanford University

Brief Summary

This study evaluates approximate number sense (ANS) in children, adolescents, and adult women with Turner syndrome compared to age-matched healthy peers. One primary aim of this project is to assess the effectiveness of an online ANS training tool in enhancing complex mathematics ability. Participants will undergo weekly training sessions in their own home. Half of the participants will complete 2 training sessions a week for 8 weeks, and the second half will complete 1 training session for 8 weeks.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-02-27
• Study First Submitted QC: 2018-03-02
• Study First Posted: 2018-03-09
• Study Start: 2022-04-01
• Primary Completion: 2022-04-02
• Study Completion: 2022-04-02
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-03
• Last Update Posted: 2022-05-09

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

• Children, adolescents, and adult women with Turner syndrome.
• Healthy controls.
• Normal or corrected to normal vision.

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Exclusion Criteria

• Major psychiatric or developmental disorder (e.g., bipolar disorder, major depression, psychotic disorders, intellectual disability, autism spectrum disorder).
• Chemical dependency
• Currently taking the following medications: antidepressant, antipsychotic, and anti-seizures drugs.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
ANS training	ANS training	-

Primary Outcome Measures

Name	Time	Method
Single and multiple-operand addition and subtraction response time	8 weeks	Average amount of time, in seconds, required to answer each question on the task.
Single and multiple-operand addition and subtraction accuracy	8 weeks	Task accuracy calculated as the percentage of trials answered correctly.

Trial Locations

Locations (1)

Center for Interdisciplinary Brain Sciences Research; 🇺🇸 Stanford, California, United States