Comparison of Reversal First versus Response First technique of Extubation for Assessing the Quality of Extubation in Patients Undergoing Elective Supratentorial Craniotomy:A Prospective observational Study
- Conditions
- Health Condition 1: G978- Other intraoperative and postprocedural complications and disorders of nervous system
- Registration Number
- CTRI/2023/02/049765
- Lead Sponsor
- Post Graduate Institute of medical education and research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Patient undergoing elective supratentorial craniotomy under general anaesthesia after adequate fasting according to standard American Society of Anaesthesiologists (ASA) guidelines
Patients belonging to ASA status 1 and 2
Guide : Dr. Hemant Bhagat
Professor, Neuroanesthesia, Department of Anesthesia, Post Graduate Institute of Medical education and research
email id : hembhagat@rediffmail.com
•Patient refusal for consent
•Anticipated difficult airway
•History of Obstructive sleep apnea
•Pregnancy, achalasia cardia, preexisting acid peptic disease/vocal cord palsy
•Uncontrolled diabetes, hypertension, recent respiratory tract infection, bronchial asthma
•Patients with pneumocephalus/ pneumoventricle.
•Patients with GCS less than 15.
•Patients with preexisting involvement of lower cranial nerves.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assess the quality of emergence score in patients extubated after attainment of consciousness and assessing response just before administration of reversal of neuromuscular block compared to the traditional technique of extubation.Timepoint: The quality of emergence score will be assessed once during extubation
- Secondary Outcome Measures
Name Time Method The hemodynamic parameters like heart rate, systolic blood pressure, diastolic blood pressure and mean blood pressure <br/ ><br>To assess the incidence of <br/ ><br>Vomiting/regurgitation <br/ ><br>Aspiration Laryngospasm/bronchospasm <br/ ><br>Postoperative bleeding into surgical drain for 24 hours <br/ ><br>Postoperative intracranial hematoma formation using computed tomography scan <br/ ><br>Neurological outcome at discharge using mRs <br/ ><br>Timepoint: The same hemodynamic parameters mentioned above will be assessed during the periextubation period i.e., at cessation of anaesthesia followed by continuous monitoring 1 min prior to extubation followed by every 1 minute for 5 mins, every 5 mins upto 15 mins and every 15 mins till one hour post extubation. <br/ ><br>vomiting and aspiration will be assessed upto 2 hours postoperatively <br/ ><br>Neurological outcome will be assessed at discharge.