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MRI measurements of the brain vessel walls in patients with an ischemic stroke or TIA.

Conditions
Atherosclerosis, stroke, TIA, intracranial, vessel wall, MRI, magnetic resonance imaging.Atherosclerose, herseninfarct, cerebraal infarct, intracraniaal, TIA, vessel wall, MRI.
Registration Number
NL-OMON22252
Lead Sponsor
niversity Medical Center Utrecht
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
100
Inclusion Criteria

Main inclusion criteria for stroke patients and TIA patients:

1. 18 years or older;

Exclusion Criteria

1. Stroke patients without occlusion of an artery of the anterior cerebral circulation on CT angiography;

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The presence or absence of intracranial atherosclerosis (intracranial vessel wall atheroma) in arteries of the anterior cerebral circulation in the studied groups (stroke patients and TIA patients).
Secondary Outcome Measures
NameTimeMethod
Characterization of the intracranial vessel wall atheroma, specifically unstable atheroma, by MR signal on multiple MRI-sequences, and assessment of clinical consequences of intracranial atherosclerosis by evaluation of standard brain imaging and neuropsychological tests.
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