MRI measurements of the brain vessel walls in patients with TIA or ischemic stroke of the posterior circulation.

Recruiting

• Conditions: Atherosclerosis; ischemic stroke; TIA; MRI

• Registration Number: NL-OMON20531
• Lead Sponsor: niversity Medical Center Utrecht, the Netherlands.

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:

1. ¡Ý 18 years of age.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:

1. Allergic reaction to gadolinium or one of the constituents of its solution for administration;

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The presence or absence of intracranial vessel wall abnormalities in arteries of the intracranial posterior circulation. Presence of atherosclerosis is defined as any irregularity of the arterial vessel wall.

Secondary Outcome Measures

Name	Time	Method
1. Number of vessel wall abnormalities in the intracranial vessel wall MRI scan at 7.0 tesla as compared to 3.0 tesla.<br><br /><br /><br>2. Characteristics of intracranial vessel wall atheroma, by discriminating different MRI signal intensities in the vessel wall atheroma.<br><br /><br /><br>3. The clinical outcome measures (e.g. occurrence of vascular events, level of handicap, current medication) collected during follow-up.