To compare anaesthetic effect of two different routes of steroid administration with local anaesthetic for upper limb surgeries.

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/01/039646
• Lead Sponsor: Department of Anaesthesiology SMS Medical College

Brief Summary

By comparing two different routes of administration of dexamethasone, perineural and intravenous with 0.5% bupivavaine for supraclavicular brachial plexus block in patients undergoing upper limb surgeries, we can compare which route provides better surgical conditions and better post operative outcome and better post operative analgesia.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-01-20
• Study Start: 2022-01-27

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• 1 Patients undergoing elective upper limb surgeries of duration 1-4 hoursd.
• 2 Patients belonging to American Society of Anesthesiologists Grade class-I and II.
• 3 Patients with weight between 40 and 80kgs.
• 4 Patients willing to give written and informed consent.

Exclusion Criteria

• 1 Patients not willing to participate in the study 2 Uncooperative patients 3 Local infection at the injection site.
• 4 History of allergy to the study drug.
• 5 Bleeding disorders, coagulopathies or any other neuropathies 6 Contra lateral diaphragmatic paralysis 7 Systemic use of corticosteroids for 2 weeks or longer within 6 months of surgery.
• 8 Patient with history of seizures, peptic ulcer disease, hepatic or renal failure, or septicaemia 9 Patient with a history of traumatic nerve injury, diabetes mellitus, or neuropathy of the surgical limb.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the difference in mean time of onset of sensory and motor block in both groups	At 5, 10, 15 and 20 minutes post procedure

Secondary Outcome Measures

Name	Time	Method
To determine the difference in duration of analgesia in both groups	Post opertaively upto 24 hours after giving block
To determine the difference in mean duration of motor block in both groups	Post operatively upto 24 hours after giving block
To determine the difference in hemodynamic parameters: (Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Blood Pressure, Spo2)	Intraoperatively upto 90 minutes and post operatively upto 24 hours
To determine the difference in percentage of cases who develop adverse effects, if any in both the groups	Upto 90 minutes intaoperatively

Trial Locations

Locations (1)

SMS Medical College, Jaipur; 🇮🇳 Jaipur, RAJASTHAN, India

SMS Medical College, Jaipur

🇮🇳Jaipur, RAJASTHAN, India

Dr Navleen Khurana

Principal investigator

8290967387

drnavleenkhurana@gmail.com