Prediction of early neurophysiological changes in patients with critical illness polyneuromyopathy
Not Applicable
- Conditions
- G62.80G72.80
- Registration Number
- DRKS00018808
- Lead Sponsor
- Klinik für Anästhesiologie, Intensiv- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 69
Inclusion Criteria
Age = 18 years, written informed consent, sufficient knowledge of German, elective cardiac surgery with heart-lung machine
Exclusion Criteria
Employees of the investigators or of the institution who are involved in the conduct of this or other clinical trials, participants who are unable to provide informed consent due to language, psychological or somatic reasons, participants with pre-existing, already diagnosed polyneuropathy, HbA1c> 8.5%
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of the incidence and the time course of the early phase of the CIPNM, assessment of risk factors for the development of a CIPNM, determination of the correlation between neurophysiology and / or nerve morphology and clinical outcome, determination of the degree of neurophysiological and morphological changes, determination of neurophysiological profiles
- Secondary Outcome Measures
Name Time Method Determination of cytokine profiles during intensive care therapy, evaluation of differences in preoperative baseline values, predictors (e.g. frailty) of patients who will develop a CIPNM in relation to neurophysiological changes