ISRCTN42061860
Completed
未知
Comparison of crystalloid-blood resuscitation with crystalloid-colloid-blood resuscitation in severe trauma patients: a randomised double-blind trial
niversity of Cape Town (South Africa)0 sites140 target enrollmentJuly 24, 2009
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Severe trauma
- Sponsor
- niversity of Cape Town (South Africa)
- Enrollment
- 140
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients suffering severe trauma requiring at least 3 litres of estimated resuscitation fluid admitted to Groote Shuur Hospital Trauma Unit
- •2\. Penetrating or blunt trauma (separately randomised)
- •3\. Aged greater than 18 years and less than 60 years, either sex
Exclusion Criteria
- •1\. Fluid overload pulmonary oedema
- •2\. Known allergy to hydroxyethyl starch
- •3\. Known pre\-existing renal failure with oliguria including anuria, severe intracranial bleeding, severe hypernatremia or severe hyperchloremia on admission
- •4\. Severe head injury from which they are unlikely to recover
- •5\. Severe crush injury
- •6\. Unrecordable blood pressure unresponsive to 2 l fluid loading
- •7\. Clinically obvious cardiac tamponade
- •8\. Neurogenic shock (high spinal)
- •9\. Known acquired immune deficiency syndrome (AIDS) or AIDS related complex
- •10\. Patients receiving dialysis treatment
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Cristalloid vs. colloid in patients with severe sepsis and septic shock.Severe sepsis or septic shock.NL-OMON21828one60
Completed
Not Applicable
Comparison of Conventional fluid Resuscitation and Bolus fluid Resuscitation in preoperative optimization of patients with Infantile Hypertrophic Pyloric stenosisInfantile Hypertrophic Pyloric StenosisPreoperative optimizationInfantile Hypertrophic Pyloric StenosisPreoperative optimizationBolus therapyOptimizationTCTR20190512002none100
Not yet recruiting
Not Applicable
Comparative study between Albumin and Normal saline for the management of ICU admitted critically ill patientsHealth Condition 1: A049- Bacterial intestinal infection, unspecifiedHealth Condition 2: O- Medical and SurgicalHealth Condition 3: A419- Sepsis, unspecified organismCTRI/2021/11/037734VIMSAR
Not yet recruiting
Phase 1
Efficacy of early fluid resuscitation combined with Chaiqin Chengqi Decoction in treatment of acute pancreatitis: a randomized controlled trial.ITMCTR2000003450West China Hospitial, Sichuan University
Completed
Not Applicable
Improvement in low blood pressure and its outcomes due to severe infections by using normal saline fluid versus human albumin fluid in patients with cirrhosisHealth Condition 1: null- Cirrhosis Patients With Sepsis Induced HypotensionHealth Condition 2: K746- Other and unspecified cirrhosis ofliverCTRI/2016/09/007246Institute of liver and Biliary Sciences308