Comparison of crystalloid-blood resuscitation with crystalloid-colloid-blood resuscitation in severe trauma patients: a randomised double-blind trial

niversity of Cape Town (South Africa)0 个研究点目标入组 140 人开始时间: 2009年7月24日最近更新: 2017年4月18日

适应症

试验速览

暂无简介。

•1. Patients suffering severe trauma requiring at least 3 litres of estimated resuscitation fluid admitted to Groote Shuur Hospital Trauma Unit
•2. Penetrating or blunt trauma (separately randomised)
•3. Aged greater than 18 years and less than 60 years, either sex

•1. Fluid overload pulmonary oedema
•2. Known allergy to hydroxyethyl starch
•3. Known pre-existing renal failure with oliguria including anuria, severe intracranial bleeding, severe hypernatremia or severe hyperchloremia on admission
•4. Severe head injury from which they are unlikely to recover
•5. Severe crush injury
•6. Unrecordable blood pressure unresponsive to 2 l fluid loading
•7. Clinically obvious cardiac tamponade
•8. Neurogenic shock (high spinal)
•9. Known acquired immune deficiency syndrome (AIDS) or AIDS related complex
•10. Patients receiving dialysis treatment
•11. Patients admitted greater than 6 hours following injury
•12. Patients who have already received non-study colloids
•13. Patients taking part in another clinical trial at the same time
•14. Patients refusing consent

发起方

niversity of Cape Town (South Africa)