Pilot Study of New Computer-based Neuropsychological Tool: Visual Tests, Touch Responses

Not Applicable

Recruiting

• Conditions: Cerebral Neurological Illness
• Interventions: Diagnostic Test: Railroad Test; Diagnostic Test: Swamp Test; Diagnostic Test: Presidents Recognition Test; Diagnostic Test: Judgment of Line Orientation; Diagnostic Test: Symbol Span subtest of the Wechsler Memory Scale-IV; Diagnostic Test: Digit Span subtest of the Wechsler Adult Intelligence Scale-I; Diagnostic Test: Reading subtest of the Wide Range Achievement Test; Diagnostic Test: Dot Counting Test

• Registration Number: NCT03502603
• Lead Sponsor: NYU Langone Health

Brief Summary

This study is aimed at investigating three new tests that will form part of a computerized tool designed to test brain/cognitive functioning. The system will be evaluated along with the tests' usability on samples of healthy controls and neurologically impaired patient participants. These new tests will be assessed with regard to reliability and validity. Reliability will be addressed through investigation of internal consistency of the test items. Validity will be evaluated relative to traditional paper-and-pencil tests and differentiation between patient and healthy participants.Each participant will complete both the computerized and paper and pencil-based tests. The results will be analyzed to see how performances on the two test types compare. The overall aim of this project is to determine if these new computerized tasks are an improvement over standard paper and pencil-based neuropsychological measures.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-04-11
• Study First Submitted QC: 2018-04-11
• Study First Posted: 2018-04-18
• Study Start: 2019-05-10
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-26
• Last Update Posted: 2024-08-27
• Primary Completion: 2024-12-16
• Study Completion: 2024-12-16

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Individuals without positive cerebral findings on neuroimaging (Non-PCF)

• Participants can be male or female and between the ages of 21 and 65 years old.
• Participants will have adequate perceptual and motor capabilities to participate in testing.

Neuroimaging-positive cerebral findings (PCF)

• Patients at NYULMC identified to have significant cerebral findings on neuroimaging.
• Participants will be male or female and between the ages of 21 and 65 years old.
• Participants will have adequate perceptual and motor capabilities to participate in testing.

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Exclusion Criteria

• Participants without adequate perceptual and motor capacities preventing them from participation in the testing.
• Participants with severe dysfunction at the level of dementia that can interfere with informed consent.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Non-CNI participants	Reading subtest of the Wide Range Achievement Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Judgment of Line Orientation	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Swamp Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Presidents Recognition Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Non-CNI participants	Presidents Recognition Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Non-CNI participants	Judgment of Line Orientation	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Non-CNI participants	Digit Span subtest of the Wechsler Adult Intelligence Scale-I	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Digit Span subtest of the Wechsler Adult Intelligence Scale-I	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Non-CNI participants	Railroad Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Non-CNI participants	Dot Counting Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Railroad Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Non-CNI participants	Swamp Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Symbol Span subtest of the Wechsler Memory Scale-IV	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Reading subtest of the Wide Range Achievement Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Cerebral neurological illness (CNI) participants	Dot Counting Test	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message
Non-CNI participants	Symbol Span subtest of the Wechsler Memory Scale-IV	Identified from the department of Rehabilitation, Psychiatry, and Medicine and referred to the research staff via in-person communication, email or staff message

Primary Outcome Measures

Name	Time	Method
Score on Railroad Test	1 Day
Score on Swamp Test	1 Day
Score on President Recognition Test	1 Day

Trial Locations

Locations (1)

New York University School of Medicine; 🇺🇸 New York, New York, United States