The Effect of Fibrinogen Injection on Bleeding in Total Knee Arthroplasty
Phase 3
Recruiting
- Conditions
- Total Knee Arthroplasty.Loose body in knee
- Registration Number
- IRCT20190222042803N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
Patients candidate of Total Knee Arthroplasty (TKA)
Age group 40-70 years
American Society of Anesthesiologists (ASA) classification I , II
Exclusion Criteria
Patients with cardiovascular diseases
Patients with anemia or bleeding disorders
Consumption of Anticoagulant medications
History of knee arthroscopy
History of deep vein thrombosis
High Body Mass Index
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-operative bleeding. Timepoint: 0, 6 and 24 hours after surgery. Method of measurement: Blood volume in Hemovac.
- Secondary Outcome Measures
Name Time Method Hemoglobin. Timepoint: 0, 6 and 24 hours after surgery. Method of measurement: Blood test.;Prothrombin time (PT). Timepoint: 0, 6 and 24 hours after surgery. Method of measurement: Blood test.;Partial thromboplastin time (PTT). Timepoint: 0, 6 and 24 hours after surgery. Method of measurement: Blood test.;Hematocrit (HCT). Timepoint: 0, 6 and 24 hours after surgery. Method of measurement: Blood test.;Plasma level of fibrinogen. Timepoint: 0, 6 and 24 hours after surgery. Method of measurement: Blood test.