Role of endothelin- and nitric oxide-system in the regulation of optic nerve head blood flow during changes in ocular perfusion pressure

Department of Clinical Pharmacology0 个研究点开始时间: 2006年1月16日最近更新: 2013年6月10日

适应症

试验速览

暂无简介。

•Men aged between 18 and 35 years, nonsmokers.
•Body mass index between 15th and 85th percentile (Must et al. 1991)
•Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant.
•Normal laboratory values unless the investigator considers an abnormality to be clinically irrelevant.
•Normal ophthalmic findings, ametropy < 1 Dpt.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years)
•F.1.3.1 Number of subjects for this age range

•Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study.
•Treatment in the previous 3 weeks with any drug.
•Symptoms of a clinically relevant illness in the 3 weeks before the first study day.
•History of hypersensitivity to the trial drug or to drugs with a similar chemical structure.
•History or presence of gastrointestinal, liver or kidney disease, or other conditions known to interfere with, distribution, metabolism or excretion of study drugs.
•Blood donation during the previous 3 weeks.

发起方

Department of Clinical Pharmacology