Effects of nutrient in Japanese subjects with knee pain: a randomized, double-blind, placebo-controlled, parallel pilot study.
- Conditions
- Knee pain
- Registration Number
- JPRN-UMIN000031558
- Lead Sponsor
- SOUKEN Laboratories
- Brief Summary
Continuous intake of active nutrient significantly lowered VAS score of knee pain. -Continuous intake of active nutrient significantly relieved knee pain and stiffness. Aging Clinical and Experimental Research (https://doi.org/10.1007/s40520-018-0953-6)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Not provided
-Subjects who have therapeutic history for at least 2 year for knee joint pain -Subjects who suffer from articular rheumatism -Subjects who suffer from liver or kidney disease -Subjects who have therapeutic history for serious liver, kidney or heart disease -Subjects who have medication for knee joint pain (anodyne, anti-inflammation) -Subjects who have therapeutic history for at least 1 year for serious locomotor system (for example, a fracture, a tendon rapture, a pulled muscle) -Subjects who take excess alcohol -Subjects who take supplement including chondroitin sulfate or glucosamine for knee joint pain in daily -Subjects who are not eligible due to physician's judgment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method VAS score of knee pain, JKOM score
- Secondary Outcome Measures
Name Time Method Blood metabolite concentrations, Blood enzyme activities