Drie aspecten in transcraniele magnetische stimulatie: Geluidsmaskering, puls intensiteit en plaatsing van de spoel.
- Conditions
- EpilepsiaTMStranscranial magnetic stimulation
- Registration Number
- NL-OMON24037
- Lead Sponsor
- Prof. dr. ir. M.J.A.M. Van PuttenUniversiteit Twente
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 21
Inclusion Criteria
1. Age between 18 and 60;
2. Patients: Focal epilepsy.
Exclusion Criteria
1. Hearing problems;
2. (Possible) pregnancy;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Our main endpoints are the presence and characteristics of the auditory evoked potential, the TMS-MEP and TMS-EEG response.<br /><br>1. Auditory evoked potential:<br /><br>A. Amplitude (microV);<br /><br>B. Latency (msec).<br /><br>2. MEP:<br /><br>A. Amplitude (mV);<br /><br>B. Latency (msec);<br /><br>C. Motor Threshold (Tesla).<br /><br>3. TMS-EEG response:<br /><br>A. Amplitude of peaks (microV);<br /><br>B. Latencies of peaks (msec).
- Secondary Outcome Measures
Name Time Method TMS-EEG response: Additional signal analysis methods, including wavelet analysis of early and late TMS-EEG responses and the spatiotemporal characteristics of the TMS-EEG response. <br><br /><br /><br>In the epilepsy patients, we will record the number of epileptic abnormalities in the EEG before and after the TMS experiment.