Efficacy of Retinal Nerve Fiber Layer (RNFL) / Ganglion Cell Layer Thickness Ratio by RT-View Utilizing Spectral -Domain Technology as a Diagnostic Predictor of Glaucoma.
- Conditions
- Primary Open Angle Glaucoma
- Registration Number
- NCT00773123
- Lead Sponsor
- Yonsei University
- Brief Summary
RT-View utilizes spectral domain technology to assess both RNFL and ganglion cell layer thickness. This study aims to correlate visual field defects in patients with glaucoma to both RNFL and ganglion cell layer thickness.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
- Evidence of retinal disease
- Neovascular glaucoma
- Secondary glaucoma due to intraocular inflammation
- Lens induced glaucoma
- Tumor induced glaucoma
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ganglion cell layer thickness 1 month
- Secondary Outcome Measures
Name Time Method Visual field defect 1 month
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link RNFL and ganglion cell layer thinning to glaucoma progression in primary open angle glaucoma patients using spectral-domain OCT?
How does the RNFL/ganglion cell layer thickness ratio compare to standard glaucoma diagnostic tests like visual field analysis and intraocular pressure measurements?
Which specific biomarkers in primary open angle glaucoma correlate most strongly with RNFL and ganglion cell layer thickness measured by RT-View spectral-domain technology?
What adverse events are associated with spectral-domain OCT imaging in glaucoma diagnosis and how do they impact patient monitoring strategies?
How do RT-View RNFL measurements compare to other OCT technologies like Cirrus HD-OCT or Stratus OCT in detecting early ganglion cell loss in primary open angle glaucoma?
Trial Locations
- Locations (1)
Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University School of Medicine
🇰🇷Seoul, Korea, Republic of
Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University School of Medicine🇰🇷Seoul, Korea, Republic ofChan Yun Kim, MD,PhDContact82-2-2228-3570kangeye@hotmail.comSung Yong Kang, MDContact82-2-2228-3570kangeye@yuhs.acChan Yun Kim, MD,PhD.Principal Investigator