Cognitive function and surgical success following pulmonary endarterectomy. A randomised controlled trial to compare deep hypothermic circulatory arrest with selective anterograde cerebral perfusio
- Conditions
- EndarterectomySurgery
- Registration Number
- ISRCTN84972261
- Lead Sponsor
- Papworth Hospital NHS Foundation Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 110
Current inclusion criteria as of 25/04/2008:
1. Patients referred for PEA
2. Aged between 18 and 80, either sex
3. Written informed consent obtained
Previous inclusion criteria:
All patients referred to Papworth hospital for PEA
Added 25/04/2008:
1. Anticipated difficulty with completion of cognitive function tests (e.g. sight or hearing impairments, physical barriers)
2. Not fluent in the English language
3. Unable to obtain informed consent
4. Patients having other concomitant surgery, e.g. coronary artery bypass grafting, valve surgery
5. Past medical history of stroke or psychiatric disorder
6. Repeat PEA
7. Patients having unacceptable risk as per investigator judgement or where a specific request for either DHCA or SACP has been made by the surgeon
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method