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临床试验/CTRI/2020/02/023466
CTRI/2020/02/023466招募中2 期

Comparison of Pressure support ventilation and T-piece ventilation during spontaneous breathing trials on successful extubation among patients on mechanical ventilation.

Johnson0 个研究点目标入组 0 人开始时间: 待定最近更新:

试验速览

阶段
2 期
状态
招募中
发起方
Johnson

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1.Patients aged 18 years or older.
  • 2.Patients undergoing mechanical ventilation for atleast 24 hours considered eligible for weaning by the following weaning criteria:
  • A.Patient who are alert and co-operative.
  • B.The resolution or improvement of the condition leading to intubation.
  • C.Hemodynamical stability, defined as systolic blood pressure between 90 and 160 mmHg and heart rate less than 140/min without vasopressors or with low doses of vasopressors.
  • D.Glasgow coma scale of 8 or greater.
  • E.Respiratory stability, defined as oxygen saturation > 90% with FiO2 < 0.5, PEEP <= 5cm H2O, respiratory rate < 30/min, spontaneous tidal volume > 5mL/kg, PF ratio > 200.
  • F.Non-copious secretions ( <3 aspirations in the last 8 hours).
  • G.Diaphragmatic thickness fraction > 28.
  • H.Rapid shallow breathing index <= 105.
  • I.Patients in spontaneous intermittent mandatory ventilation (SIMV) mode with a pressure support of 8.

排除标准

  • 1.Pregnant women.
  • 2.Patients with diaphragm paralysis.
  • 3.Patients with neuromuscular disorders.
  • 4.Patients on tracheostomy.

研究者

发起方
Johnson

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