COMPARISON OF TWO METHODS FOR WEANING A PATIENT FROM MECHANICAL VENTILATOR.
- Conditions
- Health Condition 1: G988- Other disorders of nervous systemHealth Condition 2: T449- Poisoning by, adverse effect of and underdosing of other and unspecified drugs primarily affecting the autonomic nervous systemHealth Condition 3: J969- Respiratory failure, unspecifiedHealth Condition 4: I999- Unspecified disorder of circulatory system
- Registration Number
- CTRI/2020/02/023466
- Lead Sponsor
- Johnson
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients aged 18 years or older.
2.Patients undergoing mechanical ventilation for atleast 24 hours considered eligible for weaning by the following weaning criteria:
A.Patient who are alert and co-operative.
B.The resolution or improvement of the condition leading to intubation.
C.Hemodynamical stability, defined as systolic blood pressure between 90 and 160 mmHg and heart rate less than 140/min without vasopressors or with low doses of vasopressors.
D.Glasgow coma scale of 8 or greater.
E.Respiratory stability, defined as oxygen saturation > 90% with FiO2 < 0.5, PEEP <= 5cm H2O, respiratory rate < 30/min, spontaneous tidal volume > 5mL/kg, PF ratio > 200.
F.Non-copious secretions ( <3 aspirations in the last 8 hours).
G.Diaphragmatic thickness fraction > 28.
H.Rapid shallow breathing index <= 105.
I.Patients in spontaneous intermittent mandatory ventilation (SIMV) mode with a pressure support of 8.
1.Pregnant women.
2.Patients with diaphragm paralysis.
3.Patients with neuromuscular disorders.
4.Patients on tracheostomy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method