Quadratus Lumborum Block Versus Transversus Abdominus Plane Block for Pain Management After Donor Nephrectomy

Not Applicable

Completed

• Conditions: Kidney Donor
• Interventions: Procedure: QL Block; Procedure: TAP Block

• Registration Number: NCT03476850
• Lead Sponsor: Medical University of South Carolina

Brief Summary

To evaluate quadratus lumborum block effect on post operative pain scores during the first 24 hours after surgery as compared to transversus abdominis plane block after laparoscopic donor nephrectomy patients.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2018-02-19
• Study First Submitted: 2018-02-28
• Study First Submitted QC: 2018-03-23
• Study First Posted: 2018-03-26
• Primary Completion: 2019-05-22
• Study Completion: 2019-05-22
• Results First Submitted: 2020-05-13
• Status Verified: 2020-06
• Results First Submitted QC: 2020-06-24
• Last Update Submitted: 2020-06-24
• Results First Posted: 2020-07-14
• Last Update Posted: 2020-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Patients undergoing laparoscopic assisted donor nephrectomy
• Patients that have elected to have a nerve block
• 18 years of age or older
• Patients of ASA status I - III

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Exclusion Criteria

• Chronic pain or narcotic usage during the preceding 30 days
• Infection at or near the intended needle insertion site
• Complex or altered abdominal wall anatomy
• Weight <45kg

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
QL Block	QL Block	Blocks will be performed under the supervision of a regional anesthesia attending experienced in the performance QL blocks. QL block will be performed using ropivacaine 0.375% 20ml each side for a total volume of 40cc.
TAP Block	TAP Block	Blocks will be performed under the supervision of a regional anesthesia attending experienced in the performance TAP blocks. TAP block will be performed using ropivacaine 0.375% 20ml each side for a total volume of 40cc.

Primary Outcome Measures

Name	Time	Method
Average Pain Score	24 hours post operative	NRS patient reported (number rated pain score, 0=no pain - 10=highest pain) over the first 24 hours post operative.

Secondary Outcome Measures

Name	Time	Method
Total Cumulative Opioids	72 hours	opiate consumption first 72 hours post operatively
Number of Participants With Nausea or Emesis Requiring Antiemetic Medication	24 hours	Antiemetics given in PACU. Occurrence of nausea or emesis requiring antiemetic medication administration in PACU.
Number of Participants With Block Related Complications	24 hours
Length of Stay in Post Anesthesia Care Unit (PACU)	24 hours	Duration of PACU stay.
Length of Hospital Stay	3 days	The time from surgery completion to subject meeting discharge criterion.

Trial Locations

Locations (1)

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States