To study and compare the effect of preoperative nebulized Magnesium sulphate versus Lignocaine in reducing the incidence of post-operative sore throat in patients undergoing surgery under general anaesthesia
Phase 1/2
Not yet recruiting
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2024/02/062836
- Lead Sponsor
- Supriya
- Brief Summary
We will be nebulizing patients with Magnesium sulfate 250mg and Lignocaine 100 mg over 15 minutes and then follow up patients for developing pharyngolaryngeal complications
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
ASA class I-II BMI 18.5-29.9 Undergoing elective surgeries requiring general anaesthesia with cuffed ETT of duration 60-120 minutes.
Exclusion Criteria
Patients refusal for participation in study,hemodynamically unstable pt,history of hypersensitivity to drug used,history of active or recent URTI(last 6 weeks),trauma during intubation,patients on analgesics or steroids.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate & compare the effectiveness of nebulized Magnesium sulfate & Lignocaine in: 2 hours,6 hours,12 hours, 24 hours, 48 hours a.Extubation quality score using 5 points extubation quality score. 2 hours,6 hours,12 hours, 24 hours, 48 hours b.Post extubation airway related adverse effects like cough,sore throat,hoarseness. 2 hours,6 hours,12 hours, 24 hours, 48 hours
- Secondary Outcome Measures
Name Time Method 1.To access the hemodynamic parameter during surgery & extubation. 2.To access the airway dynamics during surgery & extubation.
Trial Locations
- Locations (1)
Dr Rajendra Prasad Government Medical College Tanda Kangra Himachal Pradesh
🇮🇳Kangra, HIMACHAL PRADESH, India
Dr Rajendra Prasad Government Medical College Tanda Kangra Himachal Pradesh🇮🇳Kangra, HIMACHAL PRADESH, IndiaDr SupriyaPrincipal investigator8580991452Supriyathakur65@gmail.com