comparing effect of 1% low dose aspirin gel and 0.3% flurbiprofen gel on level of gingival sulcular fluid inflammatory marker PGE2 and on clinical signs of inflammation in periodontitis patients as an adjunct to scaling and root planing
Not Applicable
Completed
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2022/10/046282
- Lead Sponsor
- SHILPA MATHEW
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 36
Inclusion Criteria
1.Patients aged between 20-50 years from both genders.
2.No history of systemic disease
3.Patients with Probing pocket depth 4-6mm.
4.Willingness to comply with the study protocol.
Exclusion Criteria
1.Patients who are undergoing long term non steroidal anti inflammatory drug therapy.
2.Previous history of periodontal therapy within 6 months.
3.Patients on immunotherapy and hormonal therapy.
4.Patients who have received antibiotic therapy in previous 3 months.
5.Patients who are using any form of chemical plaque control agents.
6.Pregnancy or lactating women.
7.Known hypersensitivity to aspirin, flurbiprofen or any NSAIDS.
8.History of Smoking.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method resolution of clinical signs of inflammation which include reduction in bleeding on probing ,probing pocket depth and reduction in gcf inflammatory marker(PGE2) and gain in clinical attachment levelTimepoint: 30 days
- Secondary Outcome Measures
Name Time Method reduction in plaque formationTimepoint: 30 days