Cerebral hemodynamics in patients with a history of preeclampsia

• Conditions: O14.9; Pre-eclampsia, unspecified

• Registration Number: DRKS00005665
• Lead Sponsor: eurozentrum, Abteilung für Neurologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-23
• Study Completion: 2014-11-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

1. Women after at least one birth with or without preeclampsia, respectively. 2. Time interval to the last birth > 1 year and < 15 years. 3. Age 18 to 55 years. 4. Written informed consent to the study.

Exclusion Criteria

1. Pregnancy at the time of study inclusion. 2. History of brain operation or brain tumor. 3. No ultrasound window for transtemporal ultrasound. 4. Epilepsy.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
sing a one-time dopplersonographic ultrasound examination, parameters of dynamic cerebral autoregulation (phase and gain) will be evaluated.

Secondary Outcome Measures

Name	Time	Method
sing a questionnaire history of cerebrovascular risk factors (hypertension, diabetes, increased BMI) and possible ischemic cerebrovascular events will be inquired.<br>During the one-time dopplersonographic examination parameters of visual coupling (resting flow velocity, overshoot flow velocity, steady-state flow velocity) will be evaluated.