Based on resting state fMRI to explore the therapeutic effect of acupressure stimulation of ST-36-Zusanli in improving the symptoms of chronic superficial gastritis and the central-humoral-metabolic mechanism
- Conditions
- superficial gastritis
- Registration Number
- ITMCTR2022000077
- Lead Sponsor
- Radiology department of Guang'anmen Hospital of Chinese Academy of traditional Chinese medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) Participants with clinical diagnosis of chronic superficial gastritis;
(2) Participants from 18 to 75 years of age. No gender limitation.
(3) Participants who have voluntarily agreed to participate in the study and have signed written informed consent, and can cooperate with and complete the treatment and follow-up course.
(1) Patients with peptic ulcer, erosive gastritis, atrophic gastritis, severe dysplasia of gastric mucosa or suspected malignant change according to pathological diagnosis;
(2) Pathological changes of digestive system, such as liver, gall bladder and pancreas;
(3) Chronic superficial gastritis caused by HP infection;
(4) Severe liver and kidney dysfunction, serious cardiovascular and cerebrovascular diseases, and malignant tumors;
(5) Those who have received anti-inflammatory, anti-acid drugs within 3 months.
(6) Pregnant or lactating women:
(7) There are pacemakers, defibrillators and other metal products in the body, and people with claustrophobia are not suitable for MRI examination.
(8) There were visible structural abnormalities in routine head MRI.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fMRI;Symptom score;
- Secondary Outcome Measures
Name Time Method index of gastric mucosa repairment;stimulus intensity;Serum levels of inflammatory factors and gastrointestinal hormones;Intestinal microbiota;