The Effect of Tracheal Intubation on AC and DC Components of a Photoplethysmograph

Completed

• Conditions: Anesthesia Intubation Complication

• Registration Number: NCT03032939
• Lead Sponsor: University of California, San Francisco

Brief Summary

Intraoperative stress responses (vasoconstriction and changes in heart rate) and postoperative pain can be monitored using photoplethysmography (PPG). PPG measures changes in tissue volume noninvasively. Therefore it can measure acute changes in arterial diameter (vasoconstriction). PPG signal has two components, AC and DC. Effects of noxious stimuli-induced stress responses (vasoconstriction) have not been studied on the DC component of PPG. The aim of this study was to investigate the effect of a known noxious stimulus (endotracheal intubation) on both the AC and DC components of PPG.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-12-18
• Primary Completion: 2012-01-30
• Study Completion: 2015-01-30
• Status Verified: 2017-01
• Study First Submitted: 2017-01-24
• Study First Submitted QC: 2017-01-25
• Last Update Submitted: 2017-01-25
• Study First Posted: 2017-01-26
• Last Update Posted: 2017-01-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• Elective surgery
• General endotracheal anesthesia
• Over 18 years of age
• Healthy

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Exclusion Criteria

• Vascular disease
• Liver or kidney disease
• Overweight

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Photoplethysmography	within 60 seconds of intubation	changes in AC and DC components of photoplethysmography

Secondary Outcome Measures

Name	Time	Method
Pulse rate	within 60 seconds of intubation	Pulse rate from photoplethysmograph