High density EMG investigation of stimulus-driven muscle responses associated with covert orienting
Completed
- Conditions
- parkinsonismParkinson's disease10028037
- Registration Number
- NL-OMON42546
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 24
Inclusion Criteria
PD patients:
A diagnosis of idiopathic PD
Age between 45 and 70 year
No musculoskeletal abnormalities of shoulder girdle and upper limbs
Normal or corrected to normal vision;Control subjects:
Age between 45 and 70 year
No musculoskeletal abnormalities of shoulder girdle and upper limbs
Normal or corrected to normal vision
No neurological disease
Exclusion Criteria
Significant rest, postural or action tremor
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The following parameters are evaluated:<br /><br>- Amplitude and timing of short-latency muscle response (SLR) in a time window<br /><br>of 50-150 ms after stimulus presentation<br /><br>- Suppression of EMG activity, in SLR time window, during orientation to<br /><br>ipsilateral side<br /><br>- Reaction times of manual responses to visual stimuli presented<br /><br>- Error rates for reaches and anti-reaches (towards and away from presented<br /><br>stimulus, respectively)<br /><br>- Correlations between SLR and behavioral measures</p><br>
- Secondary Outcome Measures
Name Time Method <p>none</p><br>