Gene expression evaluation test in skin fibroblasts using human blood metabolites ~ex vivo test~

Not Applicable

• Conditions: o

• Registration Number: JPRN-UMIN000050826
• Lead Sponsor: TES Holdings Co., Ltd.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-04-13
• Study Completion: 2023-04-21
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

Not provided

Exclusion Criteria

[1] Individuals who used a drug to treat a disease in the past 1 month. [2] Individuals who are patient or have a history of psychiatric disease, high blood pressure, diabetes, and hyperlipidemia. [3] Individuals who have a history of serious hepatopathy, kidney damage, heart disease and hematological disease. [4] Individuals who are a patient or have a history of or endocrine disease. [5] Individuals with serious anemia. [6] Individuals whose BMI is less than 18.5kg/m2 and over 25.0kg/m2. [7] Individuals who donated blood over 200mL in the past 1 month or over 400mL in the past 3 months. [8] Individuals who have a habit of continuous intake of functional foods, health foods, supplements in the past 1 month, and who plan to consume such foods during the test period. [9] Individuals who experienced unpleasant feeling during blood drawing. [10] Individuals with drug and food allergies. [11] Individuals who are a smoker or have quit smoking for less than 6 months. [12] Individuals who excessively take alcohol (expressed in an amount of alcohol: over 30g/day). [13] Individuals who participated in other clinical studies in the past 1 month. [14] Individuals judged inappropriate for the study by the principal.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of gene expression related to moisturizing, elasticity and barrier function of human skin (Before and 30,60 minutes after ingestion of the test food.)

Secondary Outcome Measures

Name	Time	Method
*Safety [1]Hematologic test (Before and 30,60,90,180 minutes after ingestion of the test food.) [2]Blood biochemical test (Before and 30,60,90,180 minutes after ingestion of the test food.)