High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients

Not Applicable

• Conditions: Blunt Thoracic Injury; Lung Ultrasound Score

• Registration Number: NCT03430258
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

Detailed Description

This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

Study Timeline

• Status Verified: 2018-01
• Study First Submitted: 2018-01-04
• Study First Submitted QC: 2018-02-05
• Last Update Submitted: 2018-02-05
• Study First Posted: 2018-02-12
• Last Update Posted: 2018-02-12
• Study Start: 2018-03-01
• Primary Completion: 2019-03-30
• Study Completion: 2019-03-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• The trauma registry was used to identify patients with moderate to severe blunt thoracic injury (abbreviated injury scale (AIS) chest score ≥3) admitted to the ICU

Exclusion Criteria

1. had intubation and used the mechanical ventilation within 2 hours
2. had the emergency surgerys within 2 hours
3. patients can not accessed by transthoracic lung ultrasound because of the sever aerodermectasia or pneumothorax
4. the Glasgow Coma Scale <8

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.	72 hours	High-flow nasal cannula could reduce the intube rate of patients with blunt thoracic injury,and improve the the lung aeration for patients with thoracic injury

Secondary Outcome Measures

Name	Time	Method
number of days in ICU	7 days	High-flow nasal cannula could reduce the number of days for the patients treatments in ICU