Satiety related brain activation and gastric distentio
- Conditions
- algemene fysiologiesatiating effect of gastric stretching
- Registration Number
- NL-OMON42427
- Lead Sponsor
- Wageningen Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 23
* Male
* Right handed
* Age 18 * 35yr
* BMI 18.5 - 25 kg/m2
* Being healthy (self-reported)
* Having given written informed consent (see E2)
* Not meeting the inclusion criteria
* Drug use or medical conditions which may interfere with normal functioning of the digestive tract
* Drug use or medical conditions which may interfere with normal functioning of the circulatory system
Drug use or medical conditions which may lead to unreliable fMRI results (including, but not limited to neurological conditions)
* Food allergy to or unwillingness to consume the study products
* Reported unexplained weight loss or weight gain of > 5 kg in the month prior to pre-study screening
* Presence of non-removable metal objects in the mouth
* Personnel of Wageningen University, department of Human Nutrition
* Current participation in other research from the Division of Human Nutrition
* Having a contra-indication to MRI scanning
* Disliking the food items.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Increase or decrease of blood perfusion signal of brain regions </p><br>
- Secondary Outcome Measures
Name Time Method <p>Satiety related scores based on appetite questionnaires, food image<br /><br>palatability scores and ad lib intake</p><br>