MedPath

FOCUS Fatigue Outcome in Copaxone USers

Phase 4
Completed
Conditions
Multiple Sclerosis
Interventions
Registration Number
NCT00267319
Lead Sponsor
Sanofi
Brief Summary

* The study primarily investigates the effect of copaxone on fatigue during treatment, compared to baseline in patients with relapsing-remitting multiple sclerosis.

* Secondary outcome measures are:disability, relapse rate, quality of life and depression.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
111
Inclusion Criteria
  • relapsing-remitting Multiple Sclerosis (MS),
  • at least 2 relapses in previous 2 years prior to copaxone or interferon beta treatment,
  • ambulant patients i.e disability score EDSS MAX 5,5,
  • clinically stable MS
  • relapse free and steroid free at least 30 days prior to start copaxone treatment
Exclusion Criteria
  • hypersensitivity to glatiramer acetate or mannitol,
  • pregnancy,
  • fertile female not willing to use effective contraception,
  • previous treatment with copaxone

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
single groupGlatiramer acetate-
Primary Outcome Measures
NameTimeMethod
fatigue impact scaleat baseline, month 6 and month 12
Secondary Outcome Measures
NameTimeMethod
relapse rateat baseline, month 6 and month 12
quality of lifeat baseline, month 6 and month 12
depressionat baseline, month 6 and month 12
disabilityat baseline, month 6 and month 12
Adverse eventsat baseline, month 6 and month 12

Trial Locations

Locations (1)

Sanofi-Aventis

🇨🇿

Praha, Czech Republic

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