Evaluation of the Effect of Non-Surgical Periodontal Treatment in Women With Polycystic Ovary Syndrome
- Conditions
- Polycystic Ovary SyndromeGingivitis
- Registration Number
- NCT06567132
- Lead Sponsor
- Bezmialem Vakif University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria:<br><br> - Women aged 18-40 with polycystic ovary syndrome and healthy periodontium<br><br> - Women aged 18-40 with polycystic ovary syndrome and gingivitis<br><br> - Women aged 18-40 who are systemically healthy and have gingivitis<br><br> - Women aged 18-40 who are systemically healthy and have a healthy periodontium<br><br> - Presence of at least 20 permanent teeth<br><br>Exclusion Criteria:<br><br> - Receiving anti-inflammatory or antimicrobial therapy in the past three months<br><br> - Smoking and alcohol consumption<br><br> - Body mass index > 30 kg/m2<br><br> - Individuals with diabetes mellitus, hyperprolactinemia, congenital adrenal<br> hyperplasia, androgen-secreting tumors, thyroid disorders, Cushing's syndrome,<br> hypertension, liver or kidney dysfunction<br><br> - Medication that may affect metabolic criteria, such as oral contraceptive agents,<br> any steroid hormone or related preparations, hypertensive drugs and insulin<br> sensitizing drugs<br><br> - Pregnancy and breastfeeding<br><br> - Receiving periodontal treatment in the last 6 months<br><br> - Taking any medication known to affect periodontal status (e.g. phenytoin, calcium<br> antagonists, cyclosporine, coumadin, steroidal non-anti-inflammatory drugs, aspirin<br> > 81 mg)<br><br> - Active infectious diseases such as hepatitis, HIV or tuberculosis
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding on probing
- Secondary Outcome Measures
Name Time Method Interleukin-6;Interleukin-10;Annexin A1