Tolerance induction by a regulartory T cell-based cell therapy in living donor liver transplantatio
Phase 1
Recruiting
- Conditions
- non-compenzated liver cirrhosis(HBV,HCV, alcoholic, etc), primary biliary cirrhosis (PBC), primary screlosing cholangitis (PSC), hepatocellular carcinoma (HCC within Milan criteria), non-alcoholic steatohepatitis (NASH), others
- Registration Number
- JPRN-UMIN000015789
- Lead Sponsor
- Traslational Research and Clinical Trial Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
1.Recipient; 1).extrahepatic malignancy, 2). extrahepatic infection or sepsis, 3)pregnant woman, 4).sever cardio-pulmonary disease, 5). patients who are regarded as inadequate for the study by investigators 2.Donor; 1). Those with with abnormality or inadequacy in the liver as a. functional (fatty liver, autoimmune liver disease, et al), b. morhological (anomaly of hepatic artery, kepatic vein, portal vein or biliary tract), c.too small graft or remnant liver for transplantation, 2). with malignanct or infection, 3). with scychological inadequacy 4). beyond 6 degree relatives
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method