A study to investigate the safety of additional treatment with Vitamin B3 in children with Juvenile Idiopathic Arthritis (JIA)
- Conditions
- Juvenile Idiopathic Arthritis, JIA, jeugdreuma
- Registration Number
- NL-OMON23481
- Lead Sponsor
- MC Utrecht, the Netherlands
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Patients with a diagnosis of oligo-articular or poly-articular JIA with active disease in 1 or multiple joints and an indication for intra-articular corticosteroid injection.
- Age between 4 to 18 years
Exclusion Criteria
- no informed consent possible by patient/parents or caregivers
- participation in other interventional trials
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method safety, feasibility and tolerability of nicotinamide treatment
- Secondary Outcome Measures
Name Time Method - PK/PD data <br /><br>- to acquire preliminary data on the effect of nicotinamide on the function of regulatory T cells in vivo and in vitro by using surrogate parameters. <br>