Comparison of Scalp Microbiome of Healthy Women Wearing Hijab and Those Who do Not Wear Hijab

Completed

• Conditions: Microbial Colonization; Scalp--Diseases
• Interventions: Procedure: Swab

• Registration Number: NCT05267119
• Lead Sponsor: Indonesia University

Brief Summary

An observational study was performed on 48 women wearing hijab and 48 women not wearing hijab to compare the scalp microbiome.

Detailed Description

The scalp sample of all subjects was taken to be analyzed for its microbial diversity. The samples were processed with Next-Generation Sequencer and analyzed with bioinformatics analysis.

The primary outcome was the characteristics of scalp microbiome

Study Timeline

• Study Start: 2019-10-01
• Primary Completion: 2020-11-09
• Study Completion: 2020-11-09
• Status Verified: 2022-02
• Study First Submitted: 2022-02-15
• Study First Submitted QC: 2022-02-23
• Last Update Submitted: 2022-02-23
• Study First Posted: 2022-03-04
• Last Update Posted: 2022-03-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 96

Inclusion Criteria

• Healthy women
• Aged 18 years old or older who had not undergone menopause
• Consenting to the study

Exclusion Criteria

• Scalp and hair diseases (e.g. alopecia, trichotillomania, scalp infection, malignancy)
• Systemic diseases (diabetes mellitus, liver diseases, renal diseases, autoimmune diseases)
• Use of topical and oral antifungal agents
• Use of cytostatic agents
• Use of topical and oral antibiotics
• Use of topical and oral vitamin D
• Use of chemical products on hair (e.g. bleaching, permanent blow, hair coloring, hair straightener)
• Pregnancy
• Lactating
• Hypersensitivity towards basic ingredients of shampoo (e.g. synthetic detergent, conditioner, thickening agent).

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
No hijab	Swab	Women not wearing hijab whose scalp sample was taken for microbiome analysis
Hijab	Swab	Women wearing hijab whose scalp sample was taken for microbiome analysis

Primary Outcome Measures

Name	Time	Method
Alpha diversity and beta diversity of scalp microbiome	Up to 2 years	The alpha and beta diversity of scalp microbiome which is generated by bioinformatics analysis from the sample processed with Next-Generation Sequencing

Trial Locations

Locations (1)

Faculty of Medicine, Universitas Indonesia; 🇮🇩 Jakarta, Indonesia