Immediate Post-operative Recovery After Regional vs. General Anesthesia

Completed

• Conditions: Outcome
• Interventions: Other: Data mining from records

• Registration Number: NCT03047148
• Lead Sponsor: University of Zurich

Brief Summary

Early post-anesthesia status of patients emerging from surgery encompasses vital respiratory and hemodynamic parameters as well as subjective signs of well-being such as absence of nausea, vomiting and a low pain level. This investigation intends to compare the rate of postoperative complications in the 2 groups from pair matched patient records after regional anesthesia with otherwise similar patients after general anesthesia.

Detailed Description

It is still unclear whether the immediate post-operative condition of patients after surgery and anesthesia is dependent on the basic anesthesia technique (General vs. regional anesthesia). The patients' post-anesthesia presentation encompasses vital respiratory and hemodynamic parameters as well as subjective signs of well-being such as absence of nausea, vomiting and a low pain level. By pair matching of patient records after regional anesthesia with otherwise similar patients after general anesthesia (control group), the rate of postoperative complications in the 2 groups will be compared. The results of this investigation will help to answer what is the difference in complication rates and wellbeing of patients depending on their previous anesthesia. The results of this study will Show which basic anesthesia technique has more or less early complications.

Study Timeline

• Study First Submitted: 2017-01-31
• Study First Submitted QC: 2017-02-06
• Study First Posted: 2017-02-08
• Study Start: 2018-01-01
• Primary Completion: 2018-04-30
• Status Verified: 2018-05
• Study Completion: 2018-05-01
• Last Update Submitted: 2018-05-07
• Last Update Posted: 2018-05-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1880

Inclusion Criteria

• Records from regional anesthesia cases on adults which have quality control assessment data, plus the same number of matched pairs who had general anesthesia.

Exclusion Criteria

• Cases with incomplete quality control assessment data.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Regional Anesthesia	Data mining from records	Hospital records from patients who have undergone surgery in regional anesthesia.
General Anesthesia	Data mining from records	Hospital records from patients who have undergone surgery in General anesthesia.

Primary Outcome Measures

Name	Time	Method
Postoperative complications during inhospital stay up to 30 days	1 March to 30 November 2017	Number participants who had one or more cardiovascular events up to discharge or 30 days
Postoperative complications during inhospital stay up to 30 days (PONV) - Duration of pain (VAS > 3) episodes in hours; days up to discharge or max. 30 days	1 March to 30 November 2017	Number of PONV episodes up to discharge or max. 30 days Duration of PONV episodes in days; hours up to discharge or max. 30 days
Postoperative complications during inhospital stay up to 30 days (pain)	1 March to 30 November 2017	Duration of pain (VAS \> 3) episodes in hours; days up to discharge or max. 30 days

Secondary Outcome Measures

Name	Time	Method
Length of hospital stay	1 March to 30 November 2017	Length of hospital stay in days up to discharge or max. 30 days
Postoperative mortality	1 March to 30 November 2017	In-patient postoperative mortality (yes or no up to 30 days)
Total in-hospital costs	1 March to 30 November 2017	Absolute amount per case in CHF according financial department report

Trial Locations

Locations (1)

University Hospital Zurich, Institue of Anesthesiology; 🇨🇭 Zurich, ZH, Switzerland