Cranberries for urinary tract infectio

Not Applicable

Completed

• Conditions: rinary tract infection; Urological and Genital Diseases

• Registration Number: ISRCTN10399299
• Lead Sponsor: niversity of Oxford

Brief Summary

2019 protocol in https://www.ncbi.nlm.nih.gov/pubmed/31870413 (added 31/12/2019) 2021 results in https://pubmed.ncbi.nlm.nih.gov/33619202/ (added 24/02/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-01-24
• Study Completion: 2020-06-30
• Last Update Posted: 8 March 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 81

Inclusion Criteria

1. Potential participant is willing and able to give informed consent for participation in the study
2. Female aged 18 years or above

CUTI Trial only:
1. Potential participant is making contact with general practice/primary care provider with urinary symptoms suggestive of acute, uncomplicated lower urinary tract infection (namely dysuria, urgency, frequency, polyuria/nocturia, haematuria and/or suprapubic pain), which the GP would normally treat with an immediate prescription of antibiotics
2. Symptom duration of under seven days (i.e. 6 days or less)
3. Potential participant is willing to receive either an immediate or delayed antibiotic prescription

CUTI Interviews only:
1. Has experienced one or more UTIs in the past 12 months

Exclusion Criteria

CUTI Trial only:
The potential participant may not enter the study if ANY of the following apply:
1. Has taken antibiotics within the past 7 days
2. Cranberry allergy
3. Already taking cranberry products regularly
4. Known or suspected pregnancy
5. Breastfeeding
6. Warfarin user (cranberries may interact with Warfarin)
7. Unable to get a clean-catch/midstream urine sample
8. In-dwelling catheter
9. Receiving end of life care/palliative care
10. Known underlying structural urological abnormalities (including polycystic kidneys)
11. Previous urological surgery
12. Immunosuppressed [e.g. active cancer (excluding localised skin cancer), receiving chemotherapy, taking regular high dose oral steroids (> 5mg/day) , HIV infection]
13. Diabetes mellitus treated with insulin
14. Signs of clinically suspected upper UTI/pyelonephritis
15. Inability to complete symptom diary accurately (e.g. dementia or psychosis)
16. Is currently involved in an interventional research study on UTI
17. Unable to access internet/email over the next two weeks
18. Is unable to decide on the same day that they contacted a primary care provider whether they would like to participate

CUTI Interviews only:
1. Potential participant was immunosuppressed at the time of their UTI (including active cancer, receiving chemotherapy, diabetes mellitus treated with insulin or taking regular high-dose oral steroids (> 5 mg/day)
2. Potential participant has underlying urological abnormalities or has had previous urological surgery
3. Potential participant is receiving end of life care or palliative care
4. Potential participant declined to participate in the CUTI trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified